@JiiPee, thanks for the additional info.
This does seem to be the Blue Iris or network related issue if it shows “no signal” in Blue Iris. If Blue Iris is not able to get the camera data/signal fundamentally, then the Media Resource auto-refresh won’t help neither. Apparently there can be many different possibilities, but I would probably check the network, and if the camera or Blue Iris has been updated recently. (Troubleshooting the wireless stability is not always the easiest thing though. 
)